Moderate Exercise Decreases Inflammation and Oxidative Stress in Hypertension
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چکیده
منابع مشابه
Editorial Commentary Moderate Exercise Decreases Inflammation and Oxidative Stress in Hypertension But What Are the Mechanisms?
Extensive epidemiological, clinical, and experimental data indicate that physical exercise slows the progression of vascular disease and reduces cardiovascular morbidity and mortality. Physical inactivity is believed to be an independent risk factor for the development of coronary heart disease, stroke, and peripheral vascular disease. As such, regular exercise is rapidly gaining widespread adv...
متن کاملModerate exercise decreases inflammation and oxidative stress in hypertension: but what are the mechanisms?
Extensive epidemiological, clinical, and experimental data indicate that physical exercise slows the progression of vascular disease and reduces cardiovascular morbidity and mortality. Physical inactivity is believed to be an independent risk factor for the development of coronary heart disease, stroke, and peripheral vascular disease. As such, regular exercise is rapidly gaining widespread adv...
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Recently, we reported that oxidative stress decreases D1 receptor numbers and G protein activation in renal proximal tubules (RPT), resulting in diminished natriuretic response to dopamine in old rats. We tested the hypothesis that exercise in old rats will decrease oxidative stress and restore natriuretic response to D1 receptor agonist, SKF 38393. Old (23 mo) rats were subjected to rest (sede...
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Objective(s): This study aimed to investigate the effect of aerobic training on serum levels of Klotho, cardiac tissue levels of H2O2 and phosphorylation of ERK1/2 and P38 as well as left ventricular internal diameter (LVID), the left ventricle wall thickness (LVWT) and fibrosis in middle-aged rats. Materials and Methods: Forty wistar rats, including young rats (n=10, 4 month-old) and middle-ag...
متن کاملInflammation and oxidative stress markers in diabetes and hypertension
Background Inflammation and oxidative stress are important factors associated with chronic disease such as essential hypertension (HTN) and type 2 diabetes mellitus (T2DM). However, the association of inflammation and oxidative stress in HTN with T2DM as a comorbidity is inconclusive due to the multifactorial nature of these cardiometabolic diseases. Methodology The influence of pathophysiolo...
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ژورنال
عنوان ژورنال: Hypertension
سال: 2009
ISSN: 0194-911X,1524-4563
DOI: 10.1161/hypertensionaha.109.136622